OSTEONECROSE DOS MAXILARES INDUZIDA POR MEDICAMENTOS: REVISÃO DE LITERATURA

Abstract

Osteonecrosis is bone necrosis due to a lack of blood supply, and medication-related jaw osteonecrosis is a rare and serious adverse effect of antiangiogenic and/or antiresorptive therapies. This study aimed to review the literature on Medication-Induced Osteonecrosis of the Jaws, emphasizing therapeutic strategies applied in established scenarios of jaw osteonecrosis, along with exploring methods for preventing necrotic bone exposure in essential surgical intervention situations. For the active and preventive treatment of this condition, therapeutic approaches such as laser therapy, ozone therapy, hyperbaric oxygen therapy, and the use of leukocyte-platelet-rich fibrin (PRF) can be adopted. However, it is important to note that this condition lacks a defined treatment protocol due to its complex management and relatively recent origin.