DSpace JSPUI

CAR-T cell immunotherapy (Chimeric Antigen Receptor) represents a significant innovation in the treatment of refractory hematological cancers, such as leukemias and lymphomas. This approach uses genetically modified T lymphocytes to express chimeric receptors (CARs) designed to recognize and destroy tumor cells. CARs consist of a single-chain variable fragment of an antibody (ScFv) for specific antigen recognition, along with a T cell activation domain. The efficacy of CAR-T cells has be...

A IMPORTÂNCIA DA TRIAGEM DA ANEMIA FALCIFORME NA INFÂNCIA Nome dos alunos: Josimara da Silva Oliveira Batista e Keila Gomes Teixeira Nome do Orientador(a): Geaneth Resumo Esta revisão bibliográfica tem como objetivo analisar a importância da triagem neonatal para a detecção precoce da anemia falciforme e seu impacto na prevenção de complicações graves e na melhoria da qualidade de vida de crianças afetadas. O estudo revisou literatura científica relevante, utilizando bases de dados co...

The purpose of this article is to discuss a relevant topic within the scope of Family Law: the adoption of children and adolescents by same-sex couples. This is an issue of great social and legal importance today, with a qualitative approach, considering the new family configurations, the legal provisions of this adoption, the prejudices faced by these couples and the bureaucracy involved in the process, including the possibility of registration in the birth register. In Brazil, a...

In the current scenario, discussions about abortion issues have been gaining repercussions in different areas, so that there are those who argue in favor of women's freedom of choice, while others are fighting for the protection of human life. Faced with such controversy, the problem arises: Collision between fundamental and individual rights, with, on the one hand, a woman's freedom of choice, and, on the other, the life of a human being. This work analyzes the arguments of the pro-...

The main objective of this study is to analyze the issue of the unconstitutionality of requiring confession in the context of the Non-Prosecution Agreement established by Law 13.964/2019. Knowly, this institution represents a novelty in our legal system, with the primary purpose of promoting consensual justice in Brazil, following a similar approach to that adopted previously in the innovations introduced by Law 9.099/95. However, considerable challenges have already arisen regarding the...

This article aims to study consensual methods of conflict resolution, where dialogue between the parties, as well as the use of appropriate techniques, encourage the construction of a society without violence. The aim is to better understand the dynamics of conciliation and mediation hearings, where the conciliator/mediator, as a third intervener, applying the due measures, encourages the parties to reach an agreement. This article will also address the systems of consensual conflic...

The objective of this work is to analyze the characteristics and impacts of the Sentimental Swindle, its consequences before the Brazilian legal system and its reflections on patrimonial violence against women. The methodology used is that of quali-quanti research, in which a mixed approach was adopted, combining qualitative and quantitative elements. The study comprises three chapters, which address the legal configuration, concept and characteristics of the Sentimental Swindle, the rol...

This scientific article aims to delve into the fundamental rights of animals as sentient beings, recognizing their capacity to feel, experience emotions, and sensations. It also emphasizes the significance of these beings for environmental balance. In this regard, the research explores the evolution of the rights of non-human animals, addressing their recognition in both legal systems and society. Despite having their rights protected by legislation, often the rights of animals are not a...

This article seeks to understand the existing interfaces between psychology training and work in public social assistance policies, especially with regard to the professionals' appropriation of the content expressed in the technical guidelines pertinent to such policy. To this end, a selection was made based on bibliographical research on Reference Centers for Social Assistance (CRAS), an important social facility whose responsibility is to ensure that users enter the basic social protec...

The consumer society in times of great media influence has corroborated the increase in social demands related to the body, increasing body dissatisfaction and the search for the ideal body, with women being a large affected audience. The objective of the study was to identify some causes that lead women to not accept or modify their bodies, to discuss concepts relevant to the reasoning presented here and, on the other hand, to elucidate the contributions of psychology in order to reflec...

This article seeks to highlight the psychologist's role in assisting young offenders included in socio-educational measures with a view to enabling their reintegration into society. In addition, analyzing the socio-istorical and cultural context, as well as the influence of the psychosocial environment and psychic development were addressed, even if briefly, in order to contextualize the issues that precede the crime. The methodology used to write the article was through bibliograph...

This work addresses oral hygiene protocols in orointubated patients as a preventive measure for Mechanical Ventilation Aspiration Pneumonia (VAP), one of the most serious hospital infections in Intensive Care Units (ICUs). The objective was to analyze and compare different oral hygiene protocols, identifying their materials, techniques and application frequencies, aiming to support future standardization. The justification lies in the high prevalence of VAP and the lack of consensus...

Human identification is the means by which an individual's identity is determined. The forensic dentist works mainly in cases where the human being is in a serious state of putrefaction, charred, in corporal crime or accidents with a large number of victims. Teeth are body structures that can withstand extreme situations, such as high temperatures, without suffering significant deterioration. The objective of this work was to describe, through a literature review, the importance, effect...

This work aims to analyze the technical, economic and environmental solutions for implementing a micro-hydroelectric plant at Fazenda Bahia, located in the region of Teófilo Otoni, MG. The project seeks to meet local energy demand in a sustainable way, using the water potential of the watercourse present on the property. The methodology used included a case study with collection and analysis of technical data, such as average flow and head of fall, in addition to calculations for tur...

This study addresses the modeling of electrical projects using Building Information Modeling (BIM) methodology in conjunction with the Builder software. The research highlights the advantages of this integration compared to the conventional method using AutoCAD, demonstrating greater efficiency, accuracy, and integration among engineering disciplines. The BIM methodology enables integrated three-dimensional modeling and automates calculations and technical documentation, enhancing ...

The free energy market, also known as a business model that allows companies to negotiate and purchase electricity directly from generators, leaving aside the purchase from a local distributor. This type of business generally occurs between large companies and large consumers. Recently, there has been discussion of expanding this model to the residential sector, which represents a large portion of electricity consumption. With the increase in the search for alternatives to reduce el...

Renewable energy is less polluting and every day it becomes more necessary in our country and also in the world, since our planet needs a change as soon as possible so that the energy future is more efficient and sustainable. This research had as its main objective to demonstrate the technical and also economic viability with the aim of reducing expenses for public coffers, in this sense the possibility of expanding the Photovoltaic plant already installed in the 19th battalion of t...

The growing adoption of solar energy is driven by its sustainability and low pollutant emissions. However, at the end of their useful life, solar panels need to be disposed of properly to avoid negative environmental impacts. Recycling these materials is a promising alternative, as more than 90% of the components of the panels can be recovered. Despite being a clean and renewable source of energy, solar panels have a limited lifespan, typically between 25 and 30 years. The main goal ...